Tag: Pharmacology

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Saliva Therapeutic Drug Monitoring
9th Dec 2019
Introduction: Introduction Therapeutic drug monitoring (TDM) is defined as: “measuring serum concentrations of a drug in a single or multiple time points in a biological matrix after a dosage” (1). TDM is usef...

Pharmacotherapy for Heart Failure
9th Dec 2019
Introduction: Pharmacotherapy for heart failure   Epidemiology of Heart Failure Heart failure continues to be a rapidly growing global epidemic with an estimated prevalence of more than 37.7 million individuals ...

Drug Delivery with Dry Powder Aerosols
9th Dec 2019
Introduction: Delivery of therapeutic agents in the form of aerosols directly into the lungs is recently gaining attention. Among aerosol generation system, dry powder for inhalation has been an attractive area of...

Contamination Parameters in Whole Blood Samples
9th Dec 2019
Introduction: 1.0   General Introduction This thesis focuses on the development of contamination parameters for the new Beckman Coulter Ireland Inc (BCII) HbA1c Advanced Reagent. The HbA1c Advanced Reagent is us...

Case Study: Industrial Production of Riboflavin
9th Dec 2019
Introduction: Case Study: Industrial Production of Riboflavin   Introduction Riboflavin, also known as Vitamin B, is a water-soluble compound that is mainly produced through engineered strains of Ashbya gossypii ...

Enhancer of Zeste Homologue 2 in Cancer Treatments
9th Dec 2019
Introduction: The oncogene EZH2 drives tumorigenesis and metastasis through multiple mechanisms Introduction Chromatin regulators control gene expression by controlling the availability of DNA to the basal tran...

GM-CSF Inhibitors for Chronic Pain and Inflammation
9th Dec 2019
Introduction: INTRODUCTION Rheumatoid arthritis (RA) is a systemic, chronic autoimmune condition characterised by joint inflammation, that affects 1% of the UK adult population (1). The disease can have a huge imp...

Regulation of Blood Glucose
9th Dec 2019
Introduction: Introduction In healthy people, blood glucose is tightly regulated to ensure normal body function. Blood glucose is maintained at a narrow range within 3.5 to 8.00 mmol/L despite the varying demand of...