Tag: Genomics

The guides below were written by our professional writers, as a learning aid to help you with your studies. If you are looking for help with your studies, we offer a a range of services provided by fully qualified academics in your field of study.

Services

Articles

The Roles of ∆Np63 in EMT
16th Dec 2019
Introduction: Chapter 1: Introduction 1.1       p63, a member of p53 protein family 1.1.1      An overview The discovery and cloning of TP63 gene, a homolog of the tumor suppressor TP53, in 1998 has bro...

ASE Using DNA-seq and RNA-seq Data
16th Dec 2019
Introduction: ASE using DNA-seq and RNA-seq data Introduction One of the major steps in determining ASE requires identification of heterozygous biallelic variant sites. From a NGS perspective, when reads gene...

Photostability of DNA
13th Dec 2019
Introduction: Abstract Ultra-Violet (UV) radiation may result in skin cancer due to the hypothesis that DNA photostability provides a small allowance for photoreactions. DNA has been protected by the Ozone laye...

Genetic Factors for Anorexia Nervosa
13th Dec 2019
Introduction: Abstract Introduction & Background: Anorexia Nervosa (AN) is a chronic psychiatric eating disorder characterised by restricted eating, a relentless pursuit of weight loss and having a distorte...

Treating Cystic Fibrosis with Gene Therapy
12th Dec 2019
Introduction: In this dissertation we shall consider the field of gene therapy in specific relation to cystic fibrosis.  We examine the different delivery vector mechanisms that have already been explored and conc...

Advances in DNA Sequencing Technologies
12th Dec 2019
Introduction: Abstract Recent advances in DNA sequencing technologies have led to efficient methods for determining the sequence of DNA. DNA sequencing was born in 1977 when Sanger et al proposed the chain terminat...

Genetic Polymorphism Governing the CYP2D6 Cytrochrome
11th Dec 2019
Introduction: Genetic Polymorphism Governing the CYP2D6 Cytrochrome P450 Enzyme Subfamily in Drug Metabolism I. Abstract The decoding of the human genome has opened up an immense opportunity for further research i...

Haemoglobin-related Diseases Management Strategies
11th Dec 2019
Introduction: Abstract Haemoglobinopathies or inherited disorders of haemoglobin are the most common monogenic disorders in humans. Red cell transfusion is a well accepted therapy for clinical management of the mos...

Charcot-Marie-Tooth Disease (CMT) Genomics
11th Dec 2019
Introduction: Charcot-Marie-Tooth disease (CMT) is a clinically distinct autosomal dominant disease caused by a 1.5 Mb tandem duplication on chromosome 17. Only recently with the help of molecular genetic studies ...

CDEs as Gene and Oligonucleotide Carriers
11th Dec 2019
Introduction: Introduction The principle of somatic gene therapy is to introduce certain genes into selected cells to treat a genetic or acquired disease by interfering with the expression of specific proteins o...

Characterization of natural selection on gene duplicates
10th Dec 2019
Introduction: Specific Aims Gene duplication is an important source of evolutionary novelty. Various mechanisms were proposed to explain how duplicates could be retained in the genome, and there exist numerous emp...

Technological Advances in DNA Analysis
10th Dec 2019
Introduction: PROBLEM STATEMENT This research focuses on the technological advancements in DNA Analysis over the past years. There has been many changes made in the process of DNA Analysis, but with the changes, w...

Genetic Etiology of Parkinson's Disease
9th Dec 2019
Introduction: Abstract Parkinson disease (PD) is known as a common progressive neurodegenerative disease which is clinically diagnosed by the manifestation of numerous motor and nonmotor symptoms. PD is a geneti...