Tag: Neurology

Neuroblastoma Risk Factors and Incidence
16th Dec 2019
Introduction: Cancer is an abnormal growth of cells in which cells divide and proliferate in an uncontrolled way (Figure 1‑1) caused by multiple mutations and changes in gene expression. These cancerous cells in...

C1q Classical Complement Pathway Inhibition of Alzheimer’s Disease Pathogenesis
16th Dec 2019
Introduction: 1C1q Classical complement pathway inhibition: A novel strategy for the inhibition of Alzheimer’s disease pathogenesis INTRODUCTION 1.1 Alzheimer’s disease From the development of the Smallpox ...

How do Astrocytes Generate Heterodendritic Metaplasticity?
16th Dec 2019
Introduction: Introduction Metaplasticity mechanisms have been proposed to prevent excitotoxicity, help maintain synaptic transmission within a dynamic range (Abraham & Bear, 1996) and modify the threshold for...

Calcium & Chloride Channels Involved in Glioma Functions
16th Dec 2019
Introduction: There is tight interplay between Ca2+ and Cl– flux that can influence brain tumour proliferation, migration and invasion. Glioma is the predominant malignant primary brain tumour (accounts for ...

Relationship Between Neural Functioning During Stroop Task and Risky Sexual Behavior
16th Dec 2019
Introduction: Abstract Background: Research suggests that deficits in both executive functioning and trait impulsivity may play a role in risky sexual behavior.  At the neural level, differences in regulation of ...

Neural Alterations of the Visuospatial Working Memory Network in Children Born Preterm: A Systematic Review
16th Dec 2019
Introduction: Neural alterations of the Visuospatial Working Memory Network in Children Born Preterm: A Systematic Review   Abstract Today premature birth has been identified as a serious clinical and public ...

Calpain Inhibition as a Magic Bullet
16th Dec 2019
Introduction: Calpain Inhibition as a Magic Bullet Abstract: Proteases are involved in a variety of diseases including the majority of neurodegenerative and neuromuscular disorders. The role of protease inhibitors ...

Sleep Stages Classification from EEG Signal based on Stockwell Transform
16th Dec 2019
Introduction: Abstract—Sleep has essential role in physical health and good quality of life. Electroencephalogram (EEG) signal is used in studying sleep process and time-frequency transforms are increasingly uti...

Unravelling the Interplay of Sphingolipids and Tgf-β Signaling in the Human Corneal Stroma
16th Dec 2019
Introduction: Unravelling the Interplay of Sphingolipids and TGF-β signaling in the human corneal stroma Abstract Corneal fibrosis occurs after an incidence of injury to the corneal surface. This is characterize...

Do Psychopaths Have Abnormal Brains?
16th Dec 2019
Introduction: The neurobiology concept behind psychopathy has not been fully understood as of yet. There are very few studies that examine the structural and function of the brain in psychopaths. The aim of this ar...

Peripersonal Space (PPS): Self-frontier and Impact Prediction
16th Dec 2019
Introduction: Self-frontier and impact prediction Abstract: The construction of a coherent representation of our body and the mapping of the space immediately surrounding the body is really important to evolve and...

Peripersonal Space in the Brain: Self-Frontier and Impact Prediction
16th Dec 2019
Introduction: Self-frontier and impact prediction Abstract: The construction of a coherent representation of our body and the mapping of the space immediately surrounding the body is really important to evolve and ...

Investigation of Neurochemicals’ Role in Glioblastoma and Neural Stem Cells
13th Dec 2019
Introduction: Investigation of Neurochemicals’ Role in Glioblastoma and Neural Stem Cells: Characterization of Dopamine Receptor D4 Inhibition in Glioblastoma Stem Cells Abstract Neurochemicals that mediate...

Gender Differences in Neurotoxicity
12th Dec 2019
Introduction: Abstract Neurotoxicity is damage to the structure and/or function of the peripheral and central nervous systems. It is a common outcome of exposure to hundreds of environmental chemicals, which act vi...

Neurological Aspects of Pain
12th Dec 2019
Introduction: 1.1. Functional Properties of Nerve Fibres 1.1.1. Properties of Peripheral Somatic Nerves Peripheral somatic nerves consists generally of somatic-motor, autonomic-motor and sensible fibres. 1.1.1.1. S...

Fibroblast Growth Factors (FGFs) in Neural Induction
12th Dec 2019
Introduction: Abstract Neural induction represents the first stage in the formation of the vertebrate nervous system from embryonic ectoderm. Fibroblast Growth Factors (FGFs), initially identified for their mitogen...

Central Nervous System Co-signaling Pathways
11th Dec 2019
Introduction: Introduction The central nervous system (CNS) constitutes a highly specialized environment where immune activation can be detrimental. Traditionally, it was believed that the CNS is immunologically p...

Effects of TRPM2 Inhibition in Neuroprotection following Neonatal Hypoxic-Ischemic Brain Injury
11th Dec 2019
Introduction: Effects of TRPM2 Inhibition in Neuroprotection following Neonatal Hypoxic-Ischemic Brain Injury Abstract Neonatal hypoxic-ischemic (HI) brain injury is a major cause of acute mortality and chronic ...

A Potential Neurophysiological Correlate of Electric-acoustic Pitch Matching in Adult Cochlear Implant Users: Pilot Data
11th Dec 2019
Introduction: A potential neurophysiological correlate of electric-acoustic pitch matching in adult cochlear implant users: Pilot data The overall goal of this study was to identify an objective physiological cor...

Probiotics and Prebiotics Effect on Brain Development
10th Dec 2019
Introduction: Review Probiotic, prebiotic and brain development Abstract: During the last years, a number of studies have demonstrated that there are extensive bi-directional interactions between the central nervo...

Types of Stroke and Risk-Factors
10th Dec 2019
Introduction: Stroke is a leading cause of adult disability. Describe the pathological sub-types of stroke, including relevant risk factors, and differences in their outcomes. (50%) Based on their main pathologi...

Neural Circuits in Fear Extinction
10th Dec 2019
Introduction: Extinction, or the reduction of conditioned responses, occurs after multiple presentations of previously-conditioned stimuli (CS) without the presence of the unconditioned stimuli (UCS) (Milad & ...

Endoplasmic Reticulum Stress Response and Alzheimer’s Disease
10th Dec 2019
Introduction: Endoplasmic Reticulum Stress Response and Alzheimer’s Disease Abstract The endoplasmic reticulum is a vital organelle found in eukaryotic cells. It performs many functions from protein synthesis and...

Glutamate Transporter EAAT2 in the Treatment of Neurodegenerative Diseases
10th Dec 2019
Introduction: The role of glutamate transporter EAAT2 in the treatment of neurodegenerative diseases. Abstract Glutamate, also known as glutamic acid is the major amino acid in the human body and it is most abund...

GAA Repeat Expansion in FRDA
10th Dec 2019
Introduction: Friedreich ataxia (FRDA, OMIM #229300), the most common inherited ataxia, is an autosomal recessive neurodegenerative disorder. The first symptoms, which are limb and gait ataxia and loss of tendon r...