Tag: Biomedical Science

Role of Carboxypeptidase E in Regulation of Cortical Neuron Migration and Dendrite Morphology
11th Dec 2019
Introduction: Short Title: CPE regulates neurodevelopment Abstract Higher brain function relies on proper development of the cerebral cortex, including correct positioning of neurons and dendrite morphology. Disru...

A Cost-utility Analysis of Fulvestrant as Therapy for Oestrogen Receptor-positive Locally Advanced and Metastatic Breast Cancer
10th Dec 2019
Introduction: A cost-utility analysis of fulvestrant (Faslodex) as first-line therapy for oestrogen receptor-positive locally advanced and metastatic breast cancer List of Abbreviations   Abbreviation   Full te...

Wnt Signalling Pathways in Skin Development and Epidermal Stem Cells
10th Dec 2019
Introduction: Wnt Signalling Pathways in Skin Development and Epidermal Stem Cells Abstract Mammalian skin and its appendages constitute the integumentary system forming a barrier between the organism and its env...

Functional Investigation of Arabidopsis Fasciclin-Like Arabinogalactan-protein 16 (FLA16)
10th Dec 2019
Introduction: Functional investigation of Arabidopsis  Fasciclin-Like Arabinogalactan-protein 16 (FLA16)   4.1 Introduction Previous studies revealed FLA11 and FLA12 are highly expressed in the stem (Schmid, 20...

Experimental Investigation of MRR and SR in Electric Discharge Machine
10th Dec 2019
Introduction: Contents ACKNOWLEDGEMENT CERTIFICATE DECLARATION OF ORIGINALITY LIST OF FIGURE LIST OF TABLE Abstract Chapter 1. Introduction 1.1 Principle of Electric Discharge Machine(EDM) 1.2 Types of Electric D...

Role of the Gut Microbiota in Health and Disease
10th Dec 2019
Introduction: The gastrointestinal (GI) tract is colonized by a dense community of commensal microorganisms referred to as the gut microbiota [1]. Microbiota refers to the entire population of microorganisms that ...

Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications
10th Dec 2019
Introduction: Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications Abstract There is a current thrust towards the development of safe, integration-free approaches to gene therapy f...

Should Embryonic Stem Cell Research Be Allowed?
10th Dec 2019
Introduction: Contents Abstract Introduction Research Review Discussion Conclusion Evaluation Bibliography Appendices Abstract The aims of my project are to mainly to investigate stem cell research as a whole to c...

How Clinical Samples of Enterococcus Species Respond to Five Common Antibiotics
10th Dec 2019
Introduction: How clinical samples of Enterococcus species respond to five common antibiotics Abstract    Background: Species inEnterococcus genus are the cause of nosocomial infections, which are resistant to d...

Pain Induced Synaptic Plasticity in the Amygdala
10th Dec 2019
Introduction: Table of Contents Chapter 1: Introduction………………………………………….. 1.1 Components of Pain……̷...

Using EMG Muscle Signal to Control DC Motor
10th Dec 2019
Introduction: Contents Introduction Literature Review Electromyography Signal EMG Time and Frequency domain analysis Fuzzy logic classifier EMG Controller Microprocessor PWM Motor control DC Motor Chapter 1 – ...

Microglial Activation and Cancer Induced Bone Pain
10th Dec 2019
Introduction: Literature Review: Microglial Activation and Cancer Induced Bone Pain Microglial Development  Microglia are the resident macrophage-like cells of the central nervous system (CNS) and are the prima...

Peptides as Targeting and Enhancing Anticancer Delivery to Cell
10th Dec 2019
Introduction: Peptides as targeting and enhancing anticancer delivery to cell  4.1 Cell- penetrating peptides(CPP) and its Classification One of the recent advancement in the field of molecular biology that app...

Nanocarriers in Tumor Targeting Delivery System
10th Dec 2019
Introduction: Abstract Cancer has been becoming among the leading causes of mortality globally. The major challenges of conventional cancer therapy was the failure of most chemotherapeutic agents to accumulate sel...

MicroRNA-181a Inhibits Ocular Neovascularization
10th Dec 2019
Introduction: Running Title: miR-181a inhibits neovascularization Keywords: miR-181a, anti-angiogenesis, ocular neovascularization, extracellular miRNAs (ex-miRNAs)   Abstract: (240 words) Purpose: Excess angioge...

Stromal TRIM28-associated Signalling Pathway Modulation Within the Colorectal Cancer Microenvironment
10th Dec 2019
Introduction: Stromal TRIM28-associated signalling pathway modulation within the colorectal cancer microenvironment Abstract Background: Stromal gene expression patterns predict patient outcomes in colorectal canc...

Transplantation of Human Chorionic Mesenchymal Stem Cells-derived Dopaminergic Neurons
10th Dec 2019
Introduction: This study was performed with the purpose of evaluate the striatum alterations following injection of the 6-hydroxydopamine (6-OHDA). In addition, the effects of transplantation of HCMSCs-derived dopaminergic neurons into the striatum were evaluated using stereological methods....

The Mode of Action of Artemisinin and its Cellular and Molecular Bases of Resistance
10th Dec 2019
Introduction: Introduction to Special Study Project Malaria is a debilitating and life-threatening disease that affects some 91 countries worldwide. This protozoan infection caused 429,000 deaths in 2015 alone, of...

Immunobiology behind Colorectal Cancer
10th Dec 2019
Introduction: Abstract Colorectal cancer (CRC) affects a relatively large portion of the population in the United States. Approximately 160,000 people in the U.S. are diagnosed with CRC every year, and about 57,00...

Characterization of the Enzyme Phospholipase A1 and Its Role in Virulence in the Opportunistic Pathogen Acinetobacter Baumannii
10th Dec 2019
Introduction: Characterization of the enzyme Phospholipase A1 and its role in virulence in the opportunistic pathogen Acinetobacter baumannii SPECIFIC AIMS.     Septicemia and pneumonia are the two most sev...

Developing a Schistosoma Mansoni Antibody Detection with Recombinant Proteins
10th Dec 2019
Introduction: Table of Contents 1. Abstract 2. Introduction 2.1. Burden of disease 2.2. Disease control and our goal 2.3. Current tests for schistosomiasis 2.4. Next generation tests for Schistosoma mansoni ...

Flow Cytometric Analysis of TGF-β -induced Downregulation of Different Phosphatases Dependent E-cadherin cell-cell adhesion of HepG2 Cell Lines
10th Dec 2019
Introduction: Flow Cytometric Analysis of TGF-β -induced Downregulation of Different Phosphatases Dependent E-cadherin cell-cell adhesion of HepG2 Cell Lines Introduction: There are various types of Hepatocellula...

STK39 Blockage by RNA Interference Inhibits the Proliferation and Induces the Apoptosis of Renal Cell Carcinoma
10th Dec 2019
Introduction: STK39 blockage by RNA interference inhibits the proliferation and induces the apoptosis of renal cell carcinoma Abstract Aim: Renal cell carcinoma (RCC), the most frequent type of primary renal malig...

Glutamate Transporter EAAT2 in the Treatment of Neurodegenerative Diseases
10th Dec 2019
Introduction: The role of glutamate transporter EAAT2 in the treatment of neurodegenerative diseases. Abstract Glutamate, also known as glutamic acid is the major amino acid in the human body and it is most abund...

Liposomal Nanoparticles Control the Uptake of Ciprofloxacin Across Respiratory Epithelia
10th Dec 2019
Introduction: Liposomal nanoparticles control the uptake of ciprofloxacin across respiratory epithelia Keywords: Ciprofloxacin, Calu-3, liposomes, twin-stage impinger, nebulisation Abstract Rapid absorption and cl...